Infantile Bullous Pemphigoid Following Hepatitis B Vaccinations

Infantile Bullous Pemphigoid Following Vaccination.

BACKGROUND Post-vaccination infantile bullous pemphigod is a rare presentation. CASE CHARACTERISTICS A 2-month-old girl presented with widespread bullae, erosions, necrotic and targetoid lesions over body and mucosae after vaccination. Histology and direct immunofluorescence (DIF) were consistent with bullous pemphigoid. INTERVENTION Clinical remission with oral steroids and no recurrence w...

Infantile Bullous Pemphigoid: Two Case Reports and Literature Review

Bullous pemphigoid is an autoimmune sub epidermal blistering dermatosis that is uncommon in childhood. We report two cases of children with bullous pemphigoid. The first one was a case of a 4-month-old female infant, whereas the second is of a 3-month-old male infant. The two cases presented clinical and laboratory data for the confirmatory diagnosis of bullous pemphigoid. Opportunely we review...

Bullous pemphigoid

Bullous pemphigoid

Disease summary: Bullous Pemphigoid is an acquired, chronic, blistering autoimmune subepidermal bullous disease in which autoantibodies are directed against component of basement membrane zone of the skin [1]. It is characterized by formation of cutaneous bullae on the skin and mucous membrane. The pathogenesis involves migration of inflammatory cells into subepithilial tissues due to activatio...

Bullous pemphigoid.

B ullous pemphigoid is an autoimmune disease, which means that the cells in the body that normally fight infection attack the body instead. The body’s immune system is confused and makes an antibody (type of protein used to fight infection) that targets a part of the skin that normally holds it together. The attack on the skin causes blisters (firm, fluid-filled bubbles on the skin) to form. Th...